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7-Azidoheptanoic Acid (CAS 135920-28-4)
Cat. No. SC10240
⚠ This product is for research use only, not for human or veterinary use.
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Specifications
| CAS Number | 135920-28-4 |
| IUPAC Name | 7-azidoheptanoic acid |
| Synonyms | LCZC2227; FA73090; BP-44765; BUFLEAPQHWPYTO-UHFFFAOYSA-N |
| Molecular Weight | 171.20 g/mol |
| Molecular Formula | C7H13N3O2 |
| PubChem CID | 22907807 |
| SMILES | C(CCCN=[N+]=[N-])CCC(=O)O |
| Purity | >98% |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
Description
7-Azidoheptanoic Acid (CAS 135920-28-4) is a terminal-azide fatty acid linker for copper-catalyzed azide–alkyne cycloaddition (CuAAC) and strain-promoted azide–alkyne cycloaddition (SPAAC) bioconjugation. Its molecular formula is C₇H₁₃N₃O₂ with a molecular weight of 171.20 g/mol.
The compound bears a terminal aliphatic azide at the ω-position of a seven-carbon chain and a free carboxylic acid at the opposite terminus. The azide reacts selectively with terminal or strained alkynes to form a stable 1,2,3-triazole linkage under CuAAC or metal-free SPAAC conditions. The carboxylic acid enables direct amide coupling to amine-bearing substrates, supporting bifunctional linker applications.
- CuAAC and SPAAC bioconjugation of proteins, peptides, and small molecules
- Construction of azide-functionalized probes for metabolic labeling studies
- Linker assembly in PROTAC and ADC research
- Building block for azide-tagged lipid and fatty acid analogue synthesis
Each batch is analyzed by HPLC and ¹H NMR, with a Certificate of Analysis provided on shipment. Available from milligram to kilogram scale, with flexible packaging to meet R&D and scale-up requirements.
Documentation
✓ Certificate of Analysis (CoA) ✓ ¹H NMR Spectrum ✓ HPLC Chromatogram ✓ LC-MS (on request) ✓ MSDS / SDS
All analytical documentation is provided free of charge with every order. Raw spectral data files (NMR, HPLC, LC-MS) are also available on request — just mention it in your enquiry.
